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Gene RAD51D
Variant D90G
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51D D90G does not lie within any known functional domains of the Rad51d protein (UniProt.org). D90G demonstrates impaired Xrcc2 binding in culture (PMID: 30836272), but has not been fully biochemically characterized and therefore, its effect on Rad51d protein function is unknown.
Associated Drug Resistance
Category Variants Paths

RAD51D mutant RAD51D D90G

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Transcript NM_002878.4
gDNA chr17:g.35107442T>C
cDNA c.269A>G
Protein p.D90G
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002878 chr17:g.35107442T>C c.269A>G p.D90G RefSeq GRCh38/hg38
NM_001142571.2 chr17:g.35116913T>C c.269A>G p.D90G RefSeq GRCh38/hg38
NM_002878.4 chr17:g.35107442T>C c.269A>G p.D90G RefSeq GRCh38/hg38
NM_001142571.1 chr17:g.35116913T>C c.269A>G p.D90G RefSeq GRCh38/hg38
NM_002878.3 chr17:g.35107442T>C c.269A>G p.D90G RefSeq GRCh38/hg38
NM_001142571 chr17:g.35116913T>C c.269A>G p.D90G RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References