Gene Variant Detail

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Gene CTNNB1
Variant H24_Y142del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions CTNNB1 H24_Y142del results in the deletion of 119 amino acids of the Ctnnb1 protein from amino acids 24 to 142 (UniProt.org). H24_Y142del has not been characterized in the scientific literature and therefore, its effect on Ctnnb1 protein function is unknown (PubMed, Sep 2024).
Associated Drug Resistance
Category Variants Paths

CTNNB1 mutant CTNNB1 H24_Y142del

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Transcript NM_001098210.2
gDNA chr3:g.41224584_41225140del557
cDNA c.72_428del557
Protein p.H24_Y142del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006712985.2 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098209.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098209.2 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001904.4 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_006712985 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_017005738.2 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_005264886 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447481.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_005264886 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098209 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098210 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_006712985.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447483.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098210.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447480.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001098210.2 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_024453356.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447479.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447477.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_017005738.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_024453358.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001904 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
NM_001904.3 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_047447478.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_017005738 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38
XM_024453357.1 chr3:g.41224584_41225140del557 c.72_428del557 p.H24_Y142del RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References