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Gene KMT2A
Variant R3886*
Impact List nonsense
Protein Effect unknown
Gene Variant Descriptions KMT2A R3886* results in a premature truncation of the Kmt2a protein at amino acid 3886 of 3969 (UniProt.org). R3886* has not been characterized in the scientific literature and therefore, its effect on Kmt2a protein function is unknown (PubMed, Jul 2024).
Associated Drug Resistance
Category Variants Paths

KMT2A mutant KMT2A R3886*

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Transcript NM_005933.4
gDNA chr11:g.118521918C>T
cDNA c.11656C>T
Protein p.R3886*
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_005933.3 chr11:g.118521918C>T c.11656C>T p.R3886* RefSeq GRCh38/hg38
NM_005933 chr11:g.118521918C>T c.11656C>T p.R3886* RefSeq GRCh38/hg38
NM_005933.4 chr11:g.118521918C>T c.11656C>T p.R3886* RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References