NRAS R167L
Gene Variant Detail

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Gene NRAS
Variant R167L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions NRAS R167L lies within the hypervariable region of the Nras protein (UniProt.org). R167L has been identified in the scientific literature (PMID: 26343583), but has not been biochemically characterized and therefore, its effect on Nras protein function is unknown (PubMed, Jul 2025).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS R167L

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Transcript NM_002524.5
gDNA chr1:g.114708605C>A
cDNA c.500G>T
Protein p.R167L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524.4 chr1:g.114708605C>A c.500G>T p.R167L RefSeq GRCh38/hg38
NM_002524.5 chr1:g.114708605C>A c.500G>T p.R167L RefSeq GRCh38/hg38
NM_002524 chr1:g.114708605C>A c.500G>T p.R167L RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References