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Gene FLT3
Variant D358V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 D358V lies within the extracellular domain of the Flt3 protein (UniProt.org). D358V has been identified in the scientific literature (PMID: 28466600, PMID: 26118316, PMID: 21984973), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 D358V

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Transcript NM_004119.3
gDNA chr13:g.28048407T>A
cDNA c.1073A>T
Protein p.D358V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119 chr13:g.28048407T>A c.1073A>T p.D358V RefSeq GRCh38/hg38
XM_017020488.2 chr13:g.28028279T>A c.1073A>T p.D358V RefSeq GRCh38/hg38
NM_004119.2 chr13:g.28048407T>A c.1073A>T p.D358V RefSeq GRCh38/hg38
NM_004119.3 chr13:g.28048407T>A c.1073A>T p.D358V RefSeq GRCh38/hg38
XM_017020488.1 chr13:g.28028279T>A c.1073A>T p.D358V RefSeq GRCh38/hg38
XM_017020488 chr13:g.28028279T>A c.1073A>T p.D358V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References