Gene Variant Detail

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Gene HRAS
Variant A59D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS A59D lies within a GTP binding region of the Hras protein (UniProt.org). A59D has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS A59D

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Transcript NM_005343.4
gDNA chr11:g.533880G>T
cDNA c.176C>A
Protein p.A59D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_176795 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_001130442 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_176795.5 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38
NM_005343 chr11:g.533880G>T c.176C>A p.A59D RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References