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Gene | FLT3 |
Variant | T136N |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | FLT3 T136N lies within the extracellular domain of the Flt3 protein (UniProt.org). T136N has not been characterized in the scientific literature and therefore, its effect on Flt3 protein function is unknown (PubMed, Dec 2023). |
Associated Drug Resistance | |
Category Variants Paths |
FLT3 mutant FLT3 T136N |
Transcript | NM_004119.3 |
gDNA | chr13:g.28057424G>T |
cDNA | c.407C>A |
Protein | p.T136N |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_004119 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
XM_017020486.1 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
XM_017020486.2 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
NM_004119.2 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
XM_017020486 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
NM_004119.3 | chr13:g.28057424G>T | c.407C>A | p.T136N | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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