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Gene CDKN2A
Variant G35R
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions CDKN2A G35R lies within ANK repeat 1 of the Cdkn2a protein (UniProt.org). G35R results in growth inhibition similar to wild-type Cdkn2a in culture (PMID: 24659262), and therefore, is predicted to have no effect on Cdkn2a protein function.
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A G35R

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Transcript NM_000077.5
gDNA chr9:g.21974725C>T
cDNA c.103G>A
Protein p.G35R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001195132 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517675 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_058197.4 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517676 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_058197.5 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517676.2 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
XM_011517676.3 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_058197 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38
NM_000077 chr9:g.21974725C>T c.103G>A p.G35R RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References