NRAS T58_A59insTDV
Gene Variant Detail

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Gene NRAS
Variant T58_A59insTDV
Impact List insertion
Protein Effect unknown
Gene Variant Descriptions NRAS T58_A59insTDV results in the insertion of three amino acids within a GTP binding region of the Nras protein between amino acids 58 and 59 (UniProt.org). T58_A59insTDV has not been characterized in the scientific literature and therefore, its effect on Nras protein function is unknown (PubMed, Mar 2026).
Associated Drug Resistance
Category Variants Paths

NRAS mutant NRAS exon3 NRAS T58_A59insTDV

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Transcript NM_002524.5
gDNA chr1:g.114713916_114713917insACGTCTGTT
cDNA c.174_175insACAGACGTA
Protein p.T58_A59insTDV
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002524 chr1:g.114713916_114713917insACGTCTGTT c.174_175insACAGACGTA p.T58_A59insTDV RefSeq GRCh38/hg38
NM_002524.5 chr1:g.114713916_114713917insACGTCTGTT c.174_175insACAGACGTA p.T58_A59insTDV RefSeq GRCh38/hg38
NM_002524.4 chr1:g.114713916_114713917insACGTCTGTT c.174_175insACAGACGTA p.T58_A59insTDV RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
NRAS T58_A59insTDV unknown