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Gene APC
Variant T518A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC T518A lies within ARM repeat 2 of the Apc protein (UniProt.org). T518A has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC T518A

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Transcript NM_000038.6
gDNA chr5:g.112827932A>G
cDNA c.1552A>G
Protein p.T518A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038.5 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_000038 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001354903.1 chr5:g.112835062A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001354903.2 chr5:g.112835062A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001407460.1 chr5:g.112835062A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001127510 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001407458.1 chr5:g.112835062A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001407459.1 chr5:g.112835062A>G c.1552A>G p.T518A RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112827932A>G c.1552A>G p.T518A RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References