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Gene PTEN
Variant K6N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PTEN K6N lies within the lipid binding domain of the Pten protein (PMID: 25263454). K6N demonstrates a gene expression signature correlated with wild-type Pten in culture (PMID: 27147599), but has not been biochemically characterized and therefore, its effect on Pten protein function is unknown.
Associated Drug Resistance
Category Variants Paths

PTEN mutant PTEN K6N

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Transcript NM_000314.8
gDNA chr10:g.87864487A>C
cDNA c.18A>C
Protein p.K6N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000314.8 chr10:g.87864487A>C c.18A>C p.K6N RefSeq GRCh38/hg38
NM_000314.6 chr10:g.87864487A>C c.18A>C p.K6N RefSeq GRCh38/hg38
NM_000314 chr10:g.87864487A>C c.18A>C p.K6N RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries