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Gene TP53
Variant S392fs
Impact List frameshift
Protein Effect unknown
Gene Variant Descriptions TP53 S392fs results in a change in the amino acid sequence of the Tp53 protein beginning at aa 392 of 393, likely resulting in premature truncation of the functional protein (UniProt.org). S392fs has been identified in sequencing studies (PMID: 29604399), but has not been biochemically characterized and therefore, its effect on Tp53 protein function is unknown (PubMed, Sep 2023).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon11 TP53 S392fs

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Transcript NM_000546.6
gDNA chr17:g.(7669617_7669618)
cDNA c.(1174_1173)
Protein p.S392fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001126112.2 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_001126112 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_000546 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_000546.5 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_000546.6 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.(7669617_7669618) c.(1174_1173) p.S392fs RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries