Gene Variant Detail

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Gene APC
Variant A214V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC A214V lies within a coiled-coil domain of the Apc protein (UniProt.org). A214V has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC A214V

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Transcript NM_000038.6
gDNA chr5:g.112780899C>T
cDNA c.641C>T
Protein p.A214V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407448.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407469.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001127510 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354899.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354903.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407454.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354904.1 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407449.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407452.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354899.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407460.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407451.1 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_000038 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407456.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407458.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407455.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354903.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407447.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354898.2 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354896.2 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407467.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407459.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354904.2 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354898.1 chr5:g.112792516C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001354896.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38
NM_001407457.1 chr5:g.112780899C>T c.641C>T p.A214V RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References