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Gene APC
Variant Q1429R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC Q1429R lies within the beta-catenin binding and downregulation region of the Apc protein (PMID: 14672538). Q1429R has been identified in sequencing studies (PMID: 21720365), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC Q1429R

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Transcript NM_000038.6
gDNA chr5:g.112839880A>G
cDNA c.4286A>G
Protein p.Q1429R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127511.2 chr5:g.112839934A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001127511.3 chr5:g.112839934A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001127511 chr5:g.112839934A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_000038 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001127510 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112839880A>G c.4286A>G p.Q1429R RefSeq GRCh38/hg38

Filtering

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Sorting

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Molecular Profile Protein Effect Treatment Approaches
APC Q1429R unknown