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Gene FGFR1
Variant A431S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 A431S lies within the cytoplasmic domain of the Fgfr1 protein (UniProt.org). A431S has been identified in sequencing studies (PMID: 12738854), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 A431S

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Transcript NM_023110.3
gDNA chr8:g.38418367C>A
cDNA c.1291G>T
Protein p.A431S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716312.2 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_047421569.1 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013225.3 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716310.3 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716311 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716310 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716304 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013225 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716312 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716311.1 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013225.2 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001174066.2 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013223 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013224.2 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001410922.1 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716312.2 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013224 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001354369.2 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001174066 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023105.2 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716310.4 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023110 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001174066.1 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716303 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_006716311.1 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_001354369.1 chr8:g.38418355C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023105 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
NM_023105.3 chr8:g.38417411C>A c.1291G>T p.A431S RefSeq GRCh38/hg38
XM_017013221 chr8:g.38418367C>A c.1291G>T p.A431S RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
FGFR1 A431S unknown