FGFR1 K655I
Gene Variant Detail

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Gene FGFR1
Variant K655I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 K655I lies within the protein kinase domain of the Fgfr1 protein (UniProt.org). K655I has been identified in the scientific literature (PMID: 36639714, PMID: 39169587), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Dec 2025).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 K655I

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Transcript NM_023110.3
gDNA chr8:g.38414792T>A
cDNA c.1964A>T
Protein p.K655I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_023110.2 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
NM_001174064 chr8:g.38414612_38414613delCTinsGA c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_017013221 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
NM_001354368.1 chr8:g.38413966_38413967delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
NM_023110 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_006716304 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_017013228 chr8:g.38413966_38413967delCTinsGA c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_011544448 chr8:g.38414205_38414206delCTinsGA c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_006716303 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_011544448.1 chr8:g.38414205_38414206delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
NM_001354368.2 chr8:g.38413966_38413967delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
NM_001174064.2 chr8:g.38414612_38414613delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_011544448.2 chr8:g.38414205_38414206delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38414792T>A c.1964A>T p.K655I RefSeq GRCh38/hg38
NM_001174064.1 chr8:g.38414612_38414613delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38
XM_047421574.1 chr8:g.38413966_38413967delAGinsTC c.1964_1965delAGinsTC p.K655I RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries