Gene Variant Detail

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Gene FGFR1
Variant P252R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 P252R lies within the extracellular domain of the Fgfr1 protein (UniProt.org). P252R (corresponding to P160R in Xenopus) results in kinase activity similar to wild-type Fgfr1 but increased ligand binding in an in vivo assay (PMID: 8798788), and therefore, its effect on Fgfr1 protein function is unknown.
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 P252R

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Transcript NM_023110.3
gDNA chr8:g.38424690G>C
cDNA c.755C>G
Protein p.P252R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006716304 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_006716303 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_017013221 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_023110 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_047421570.1 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_001174063 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_017013222.2 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_017013222 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_001174063.1 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_017013221.1 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
NM_001174063.2 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38424690G>C c.755C>G p.P252R RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries