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Gene FGFR1
Variant S430F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR1 S430F lies within the cytoplasmic domain of the Fgfr1 protein (UniProt.org). S430F has been identified in sequencing studies (PMID: 22810696), but has not been biochemically characterized and therefore, its effect on Fgfr1 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

FGFR1 mutant FGFR1 S430F

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Transcript NM_023110.3
gDNA chr8:g.38418369G>A
cDNA c.1289C>T
Protein p.S430F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017013221.1 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716303 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
NM_023110.2 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716304 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
NM_023110.3 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716303.3 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_017013224.2 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
NM_001354369.1 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
XM_017013221.2 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_017013225.3 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
NM_023110 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_017013221 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716303.4 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716304.2 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
XM_006716304.1 chr8:g.38418369G>A c.1289C>T p.S430F RefSeq GRCh38/hg38
NM_001354369.2 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
XM_047421569.1 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
NM_001410922.1 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38
XM_017013225.2 chr8:g.38418357_38418358delAGinsTT c.1288_1289delAGinsTT p.S430F RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References