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Gene FGFR2
Variant D479N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 D479N lies within the cytoplasmic domain of the Fgfr2 protein (UniProt.org). D479N has been identified in sequencing studies (PMID: 25035393), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 D479N

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Transcript NM_000141.5
gDNA chr10:g.121503794C>T
cDNA c.1435G>A
Protein p.D479N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141.5 chr10:g.121503794C>T c.1435G>A p.D479N RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121503794C>T c.1435G>A p.D479N RefSeq GRCh38/hg38
NM_000141 chr10:g.121503794C>T c.1435G>A p.D479N RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References