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Gene FGFR2
Variant E470Q
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 E470Q lies within the cytoplasmic domain of the Fgfr2 protein (UniProt.org). E470Q has been identified in sequencing studies (PMID: 25035393), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 E470Q

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Transcript NM_000141.5
gDNA chr10:g.121503821C>G
cDNA c.1408G>C
Protein p.E470Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141 chr10:g.121503821C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121503821C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
NM_001144916.1 chr10:g.121496642C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121503821C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
XM_024447891.1 chr10:g.121496702C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
XM_006717712 chr10:g.121496702C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
NM_001144916 chr10:g.121496642C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
XM_024447891.2 chr10:g.121496702C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38
NM_001144916.2 chr10:g.121496642C>G c.1408G>C p.E470Q RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Protein Effect Treatment Approaches
FGFR2 E470Q unknown