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Gene FGFR2
Variant F276V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 F276V lies within Ig-like C2-type domain 3 of the Fgfr2 protein (UniProt.org). F276V has been identified in sequencing studies (PMID: 24578066), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon7 FGFR2 F276V

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Transcript NM_000141.5
gDNA chr10:g.121520092A>C
cDNA c.826T>G
Protein p.F276V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001144917.1 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001144913 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001320658 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_001144917 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_022970 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38
NM_000141 chr10:g.121520092A>C c.826T>G p.F276V RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References