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Gene FGFR2
Variant G583V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 G583V lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). G583V has been identified in sequencing studies (PMID: 22980975, PMID: 26960398), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 G583V

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Transcript NM_000141.5
gDNA chr10:g.121496647C>A
cDNA c.1748G>T
Protein p.G583V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001144918.1 chr10:g.121485491C>A c.1748G>T p.G583V RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121496647C>A c.1748G>T p.G583V RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121496647C>A c.1748G>T p.G583V RefSeq GRCh38/hg38
NM_001144918 chr10:g.121485491C>A c.1748G>T p.G583V RefSeq GRCh38/hg38
NM_000141 chr10:g.121496647C>A c.1748G>T p.G583V RefSeq GRCh38/hg38
NM_001144918.2 chr10:g.121485491C>A c.1748G>T p.G583V RefSeq GRCh38/hg38

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries