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Gene FGFR2
Variant P253S
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 P253S lies within the extracellular domain of the Fgfr2 protein (UniProt.org). P253S has been identified in sequencing studies (PMID: 11781872), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon7 FGFR2 P253S

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Transcript NM_000141.5
gDNA chr10:g.121520161G>A
cDNA c.757C>T
Protein p.P253S
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001320658 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_000141 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144917 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144913 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_022970 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121520161G>A c.757C>T p.P253S RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR2 P253S unknown