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Gene FGFR2
Variant Q289P
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 Q289P lies within Ig-like C2-type domain 3 of the Fgfr2 protein (UniProt.org). Q289P has been identified in sequencing studies (PMID: 19066959, PMID: 16526917), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon7 FGFR2 Q289P

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Transcript NM_000141.5
gDNA chr10:g.121520052T>G
cDNA c.866A>C
Protein p.Q289P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001144913 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001144917 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_022970 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001320658 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_000141 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121520052T>G c.866A>C p.Q289P RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References