Gene Variant Detail

Contact

Missing content? – Request curation!

Request curation for specific Genes, Variants, or PubMed publications.

Have questions, comments, or suggestions? - Let us know!

Email us at : ckbsupport@genomenon.com

Gene FGFR2
Variant S252F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 S252F lies within the extracellular domain of the Fgfr2 protein (UniProt.org). S252F has been identified in sequencing studies (PMID: 16418739), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon7 FGFR2 S252F

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Transcript NM_000141.5
gDNA chr10:g.121520162_121520163delCGinsTT
cDNA c.755_756delCGinsTT
Protein p.S252F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141 chr10:g.121520162_121520163delCGinsAA c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144917 chr10:g.121520162_121520163delCGinsAA c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144913 chr10:g.121520162_121520163delCGinsAA c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001320658 chr10:g.121520162_121520163delCGinsAA c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_022970 chr10:g.121520162_121520163delCGinsAA c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121520162_121520163delCGinsTT c.755_756delCGinsTT p.S252F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References