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Gene FGFR2
Variant S347C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 S347C lies within Ig-like C2-type domain 3 of the Fgfr2 protein (UniProt.org). S347C has been identified in sequencing studies (PMID: 12544231), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 S347C

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Transcript NM_000141.5
gDNA chr10:g.121517363G>C
cDNA c.1040C>G
Protein p.S347C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001144919 chr10:g.121503926T>A c.1039A>T p.S347C RefSeq GRCh38/hg38
NM_001144915.1 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144918 chr10:g.121503838G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144918.2 chr10:g.121503838G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144915.2 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001320658 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_000141 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_023029 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144919.1 chr10:g.121503926T>A c.1039A>T p.S347C RefSeq GRCh38/hg38
NM_023029.2 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144918.1 chr10:g.121503838G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144915 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_023029.2 chr10:g.121503922G>C c.1040C>G p.S347C RefSeq GRCh38/hg38
NM_001144919.2 chr10:g.121503926T>A c.1039A>T p.S347C RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121517363G>C c.1040C>G p.S347C RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References