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Gene FGFR2
Variant T341P
Impact List missense
Protein Effect gain of function
Gene Variant Descriptions FGFR2 T341P lies within the Ig-like C2-type domain 3 of the Fgfr2 protein (UniProt.org). T341P results in increased phosphorylation of Fgfr2 and is transforming in cell culture (PMID: 9539778).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 act mut FGFR2 T341P

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Transcript NM_000141.5
gDNA chr10:g.121517382T>G
cDNA c.1021A>C
Protein p.T341P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000141.4 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_000141 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144919 chr10:g.121515119T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144919.1 chr10:g.121515119T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121503860T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144917 chr10:g.121503860T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001320658.1 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144919.2 chr10:g.121515119T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121503860T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38
NM_001320658 chr10:g.121517382T>G c.1021A>C p.T341P RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries