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Gene FGFR3
Variant H349Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR3 H349Y lies within Ig-like C2-type domain 3 of the Fgfr3 protein (UniProt.org). H349Y has been identified in the scientific literature (PMID: 29656465), but has not been biochemically characterized and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 H349Y

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Transcript NM_000142.5
gDNA chr4:g.1803806C>T
cDNA c.1045C>T
Protein p.H349Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006713873.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_006713872 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513420.2 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_001354810.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_047449823.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_000142.5 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_001354810.2 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_047449822.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_047449824.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_001354809.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_006713873.2 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513422.2 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_006713873 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513420.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_001354809.2 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513422 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513420 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
XM_011513422.1 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38
NM_000142 chr4:g.1803806C>T c.1045C>T p.H349Y RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR3 H349Y unknown