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Gene FGFR3
Variant K413N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR3 K413N lies within the cytoplasmic domain of the Fgfr3 protein (UniProt.org). K413N has been identified in the scientific literature (PMID: 25056374), but has not been biochemically characterized and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 K413N

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Transcript NM_000142.5
gDNA chr4:g.1804493G>C
cDNA c.1239G>C
Protein p.K413N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000142 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_001354809.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513422 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_047449823.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513422.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513420.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513420.2 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_006713873 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_047449824.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513422.2 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_000142.5 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_001354809.2 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_047449822.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_006713872 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_006713873.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_001354810.2 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
NM_001354810.1 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_011513420 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38
XM_006713873.2 chr4:g.1804493G>C c.1239G>C p.K413N RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References