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Gene FGFR3
Variant N540V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR3 N540V lies within the protein kinase domain of the Fgfr3 protein (UniProt.org). N540V has not been characterized in the scientific literature and therefore, its effect on Fgfr3 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

FGFR3 mutant FGFR3 N540V

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Transcript NM_000142.5
gDNA chr4:g.1805642_1805643delAAinsGT
cDNA c.1618_1619delAAinsGT
Protein p.N540V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047449824.1 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713873 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713870.2 chr4:g.1805633_1805634delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
NM_000142.4 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713873.2 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
NM_000142 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713873.1 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_047449821.1 chr4:g.1805633_1805634delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_047449823.1 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713870.1 chr4:g.1805633_1805634delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
XM_006713870 chr4:g.1805633_1805634delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38
NM_000142.5 chr4:g.1805642_1805643delAAinsGT c.1618_1619delAAinsGT p.N540V RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR3 N540V unknown