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Gene ROS1
Variant G365A
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 G365A lies within the extracellular domain of the Ros1 protein (UniProt.org). G365A has been identified in sequencing studies (PMID: 28524162), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 G365A

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Transcript NM_002944.3
gDNA chr6:g.117394232C>G
cDNA c.1094G>C
Protein p.G365A
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011536051.3 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011172 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011173.1 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_011536051 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011173 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011173.2 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_011536051.2 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
NM_002944 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011172.2 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38
XM_017011172.1 chr6:g.117394232C>G c.1094G>C p.G365A RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References