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Gene ROS1
Variant S653F
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 S653F lies within fibronectin type-III domain 3 of the Ros1 protein (UniProt.org). S653F has been identified in the scientific literature (PMID: 29665843, PMID: 37655099), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 S653F

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Transcript NM_002944.3
gDNA chr6:g.117387836G>A
cDNA c.1958C>T
Protein p.S653F
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002944 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536053.2 chr6:g.117386909G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536053 chr6:g.117386909G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536051.3 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536051.2 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536051 chr6:g.117387836G>A c.1958C>T p.S653F RefSeq GRCh38/hg38
XM_011536053.3 chr6:g.117386909G>A c.1958C>T p.S653F RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries