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Gene IDH2
Variant R353fs
Impact List frameshift
Protein Effect unknown
Gene Variant Descriptions IDH2 R353fs results in a change in the amino acid sequence of the Idh2 protein beginning at aa 353 of 452, likely resulting in premature truncation of the functional protein (UniProt.org). R353fs has not been characterized in the scientific literature and therefore, its effect on Idh2 protein function is unknown (PubMed, Apr 2024).
Associated Drug Resistance
Category Variants Paths

IDH2 mutant IDH2 R353fs

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Transcript NM_002168.4
gDNA chr15:g.(90085298_90085299)
cDNA c.(1057_1056)
Protein p.R353fs
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002168 chr15:g.(90085298_90085299) c.(1057_1056) p.R353fs RefSeq GRCh38/hg38
NM_002168.3 chr15:g.(90085298_90085299) c.(1057_1056) p.R353fs RefSeq GRCh38/hg38
NM_002168.4 chr15:g.(90085298_90085299) c.(1057_1056) p.R353fs RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries