ROS1 S32I
Gene Variant Detail

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Gene ROS1
Variant S32I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 S32I lies within the extracellular domain of the Ros1 protein (UniProt.org). S32I has been identified in sequencing studies (PMID: 26960398), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Aug 2025).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 S32I

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Transcript NM_002944.3
gDNA chr6:g.117425562C>A
cDNA c.95G>T
Protein p.S32I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_006715548.4 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536053.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536057.4 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536055 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536051.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536053 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536056.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_006715548 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536053.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_047419231.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536050.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536049.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011172.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011173.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
NM_001378891.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536058.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536049.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_047419232.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536054.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
NM_002944 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
NM_001378902.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011173 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536056.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536058 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536055.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536050 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
NM_002944.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536054.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536049 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011172.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536052.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536057 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_006715548.5 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011172 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536050.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536051.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536051 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536057.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536052 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536055.2 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536054 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536056 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_017011173.1 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38
XM_011536058.3 chr6:g.117425562C>A c.95G>T p.S32I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References