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| Gene | ROS1 |
| Variant | V1979E |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ROS1 V1979E lies within the protein kinase domain of the Ros1 protein (UniProt.org). V1979E has been identified in sequencing studies (PMID: 26960398), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Oct 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
ROS1 mutant ROS1 V1979E |
| Transcript | NM_002944.3 |
| gDNA | chr6:g.117319872A>T |
| cDNA | c.5936T>A |
| Protein | p.V1979E |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |