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| Gene | HRAS |
| Variant | N26S |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | HRAS N26S does not lie within any known functional domains of the Hras protein (UniProt.org). N26S has been identified in sequencing studies (PMID: 28229982, PMID: 26960398), but has not been biochemically characterized and therefore, its effect on Hras protein function is unknown (PubMed, Sep 2025). |
| Associated Drug Resistance | |
| Category Variants Paths |
HRAS mutant HRAS N26S |
| Transcript | NM_005343.4 |
| gDNA | chr11:g.534246T>C |
| cDNA | c.77A>G |
| Protein | p.N26S |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_176795.5 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_005343 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_176795 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_001130442 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_005343.3 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_001130442.2 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_176795.4 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_005343.4 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| NM_001130442.3 | chr11:g.534246T>C | c.77A>G | p.N26S | RefSeq | GRCh38/hg38 |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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