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Gene FGFR2
Variant R165W
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FGFR2 R165W lies within Ig-like C2-type domain 2 of the Fgfr2 protein (UniProt.org). R165W has been identified in sequencing studies (PMID: 27147599), but has not been biochemically characterized and therefore, its effect on Fgfr2 protein function is unknown (PubMed, Nov 2024).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 exon5 FGFR2 R165W

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Transcript NM_000141.5
gDNA chr10:g.121551421G>A
cDNA c.493C>T
Protein p.R165W
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001320658.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_022970.4 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_000141 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_022970 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144917 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144914 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144917.2 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144913.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144914.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_022970.3 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144914.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144917.1 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001320658 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001144913 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38
NM_001320658.2 chr10:g.121551421G>A c.493C>T p.R165W RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References