Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
| Gene | KDR |
| Variant | T771R |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | KDR (VEGFR2) T771R lies within the transmembrane domain of the Kdr (Vegfr2) protein (UniProt.org). T771R has been identified in the scientific literature (PMID: 26422291, PMID: 19723655, PMID: 32123305), but has not been biochemically characterized and therefore, its effect on Kdr (Vegfr2) protein function is unknown (PubMed, Apr 2026). |
| Associated Drug Resistance | |
| Category Variants Paths |
KDR mutant KDR T771R |
| Transcript | NM_002253.4 |
| gDNA | chr4:g.55098758G>C |
| cDNA | c.2312C>G |
| Protein | p.T771R |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_002253.4 | chr4:g.55098758G>C | c.2312C>G | p.T771R | RefSeq | GRCh38/hg38 |
| NM_002253 | chr4:g.55098758G>C | c.2312C>G | p.T771R | RefSeq | GRCh38/hg38 |
| NM_002253.3 | chr4:g.55098758G>C | c.2312C>G | p.T771R | RefSeq | GRCh38/hg38 |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|