Gene Variant Detail

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Gene HRAS
Variant D47E
Impact List missense
Protein Effect unknown
Gene Variant Descriptions HRAS D47E does not lie within any known functional domains of the Hras protein (UniProt.org). D47E has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

HRAS mutant HRAS D47E

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Transcript NM_005343.4
gDNA chr11:g.533915A>C
cDNA c.141T>G
Protein p.D47E
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001130442 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_001130442.2 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_005343.4 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_005343 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_176795.5 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_176795 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_001130442.3 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_005343.3 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38
NM_176795.4 chr11:g.533915A>C c.141T>G p.D47E RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References