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Gene | HRAS |
Variant | D47E |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | HRAS D47E does not lie within any known functional domains of the Hras protein (UniProt.org). D47E has not been characterized in the scientific literature and therefore, its effect on Hras protein function is unknown (PubMed, Feb 2024). |
Associated Drug Resistance | |
Category Variants Paths |
HRAS mutant HRAS D47E |
Transcript | NM_005343.4 |
gDNA | chr11:g.533915A>C |
cDNA | c.141T>G |
Protein | p.D47E |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_001130442 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_001130442.3 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_001130442.2 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_005343 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_005343.4 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_176795.4 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_176795 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_176795.5 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
NM_005343.3 | chr11:g.533915A>C | c.141T>G | p.D47E | RefSeq | GRCh38/hg38 |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
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