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Gene JAK3
Variant F569Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions JAK3 F569Y lies within protein kinase domain 1 of the Jak3 protein (UniProt.org). F569Y has not been characterized in the scientific literature and therefore, its effect on Jak3 protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

JAK3 mutant JAK3 F569Y

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Transcript NM_000215.4
gDNA chr19:g.17837209A>T
cDNA c.1706T>A
Protein p.F569Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047438786.1 chr19:g.17837209A>T c.1706T>A p.F569Y RefSeq GRCh38/hg38
NM_000215.4 chr19:g.17837209A>T c.1706T>A p.F569Y RefSeq GRCh38/hg38
NM_000215.3 chr19:g.17837209A>T c.1706T>A p.F569Y RefSeq GRCh38/hg38
XM_011527991.3 chr19:g.17837209A>T c.1706T>A p.F569Y RefSeq GRCh38/hg38
NM_000215 chr19:g.17837209A>T c.1706T>A p.F569Y RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References