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Gene | ROS1 |
Variant | E1902K |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 E1902K lies within the cytoplasmic domain of the Ros1 protein (UniProt.org). E1902K has been identified in the scientific literature (PMID: 29642553, PMID: 34271921), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 E1902K |
Transcript | NM_002944.3 |
gDNA | chr6:g.117321332C>T |
cDNA | c.5704G>A |
Protein | p.E1902K |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944.2 | chr6:g.117321332C>T | c.5704G>A | p.E1902K | RefSeq | GRCh38/hg38 |
NM_002944 | chr6:g.117321332C>T | c.5704G>A | p.E1902K | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117321332C>T | c.5704G>A | p.E1902K | RefSeq | GRCh38/hg38 |
NM_001378902.1 | chr6:g.117321314C>T | c.5704G>A | p.E1902K | RefSeq | GRCh38/hg38 |
Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
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