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Gene APC
Variant P1076L
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC P1076L lies within the beta-catenin binding domain of the Apc protein (PMID: 14672538). P1076L has not been characterized in the scientific literature and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC P1076L

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Transcript NM_000038.6
gDNA chr5:g.112838821C>T
cDNA c.3227C>T
Protein p.P1076L
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001407457.1 chr5:g.112839070C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001354898.2 chr5:g.112838896C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001407455.1 chr5:g.112839070C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001127510 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001407456.1 chr5:g.112839070C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001354898.1 chr5:g.112838896C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_000038 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112838821C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38
NM_001407454.1 chr5:g.112839070C>T c.3227C>T p.P1076L RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References