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Gene PIK3CA
Variant T1025K
Impact List missense
Protein Effect unknown
Gene Variant Descriptions PIK3CA T1025K lies within the PI3K/PI4K domain of the Pik3ca protein (UniProt.org). T1025K has been identified in sequencing studies (PMID: 27672108), but has not been biochemically characterized and therefore, its effect on Pik3ca protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

PIK3CA mutant PIK3CA exon21 PIK3CA T1025K

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Transcript NM_006218.4
gDNA chr3:g.179234231_179234232delCCinsAG
cDNA c.3074_3075delCCinsAG
Protein p.T1025K
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011512894 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
NM_006218.3 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
NM_006218.4 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
XM_006713658 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
XM_006713658.5 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
NM_006218 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
XM_006713658.4 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38
XM_011512894.2 chr3:g.179234231_179234232delCCinsAG c.3074_3075delCCinsAG p.T1025K RefSeq GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries