DNMT3A G302del - Gene Variant Detail

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Gene DNMT3A
Variant G302del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions DNMT3A G302del results in the deletion of an amino acid in the PWWP domain of the Dnmt3a protein at amino acid 302 (UniProt.org). G302del has been identified in the scientific literature (PMID: 24659740), but has not been biochemically characterized and therefore, its effect on Dnmt3a protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

DNMT3A mutant DNMT3A G302del

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Transcript NM_022552.5
gDNA chr2:g.25247699_25247701delGCC
cDNA c.904_906delGGC
Protein p.G302delG
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_017003526 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
NM_001320893.1 chr2:g.25246227_25246229delGGC c.904_906delGCC p.A302delA RefSeq GRCh38/hg38
NM_175629 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
XM_011532667.4 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
NM_001375819.1 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
XM_047443597.1 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
XM_005264175.6 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
XM_047443592.1 chr2:g.25246697_25246699delACC c.904_906delGTG p.V302delV RefSeq GRCh38/hg38
XM_011532664.2 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
NM_022552.4 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
NM_175629.2 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
XM_047443599.1 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
XM_047443594.1 chr2:g.25246203_25246205delCGC c.905_907delCGG p.A302delA RefSeq GRCh38/hg38
XM_047443596.1 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
NM_022552.5 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
NM_022552 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
XM_011532662.3 chr2:g.25247120_25247122delGCA c.904_906delTGC p.C302delC RefSeq GRCh38/hg38
XM_017003526.1 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
XM_011532666.3 chr2:g.25246061_25246063delCGC c.905_907delGGC p.R302delR RefSeq GRCh38/hg38
XM_011532664.3 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
NM_153759.3 chr2:g.25246021_25246023delCTC c.905_907delAGG p.E302delE RefSeq GRCh38/hg38
XM_047443593.1 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
XM_005264175.5 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
XM_011532664 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
NM_175629.2 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38
XM_017003526.2 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302delG RefSeq GRCh38/hg38
XM_017003527.2 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
XM_047443598.1 chr2:g.25244632_25244634delCGC c.904_906delGCG p.A302delA RefSeq GRCh38/hg38
XM_005264175 chr2:g.25247699_25247701delGCC c.904_906delGGC p.G302del RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References