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Gene FLT3
Variant G282R
Impact List missense
Protein Effect unknown
Gene Variant Descriptions FLT3 G282R lies within the Ig-like C2-type domain of the Flt3 protein (UniProt.org). G282R has been identified in sequencing studies (PMID: 24728327), but has not been biochemically characterized and therefore, its effect on Flt3 protein function is unknown (PubMed, Dec 2023).
Associated Drug Resistance
Category Variants Paths

FLT3 mutant FLT3 G282R

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Transcript NM_004119.3
gDNA chr13:g.28049673C>T
cDNA c.844G>A
Protein p.G282R
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_004119 chr13:g.28049673C>T c.844G>A p.G282R RefSeq GRCh38/hg38
NM_004119.2 chr13:g.28049673C>T c.844G>A p.G282R RefSeq GRCh38/hg38
NM_004119.3 chr13:g.28049673C>T c.844G>A p.G282R RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References