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Gene FGFR2
Variant V564T
Impact List missense
Protein Effect no effect - predicted
Gene Variant Descriptions FGFR2 V564T lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). V564T results in activation rates similar to wild-type Fgfr2 in cell culture (PMID: 21454610), and therefore, is predicted to have no effect on Fgfr2 protein function.
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 V564T

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Transcript NM_000141.5
gDNA chr10:g.121496704_121496705delGTinsAC
cDNA c.1690_1691delGTinsAC
Protein p.V564T
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_024447887.1 chr10:g.121488076_121488077delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_001144916 chr10:g.121487375_121487376delACinsGT c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_001144916.1 chr10:g.121487375_121487376delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_001144916.2 chr10:g.121487375_121487376delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_000141 chr10:g.121496704_121496705delACinsGT c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
XM_024447887.2 chr10:g.121488076_121488077delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_000141.5 chr10:g.121496704_121496705delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38
NM_000141.4 chr10:g.121496704_121496705delGTinsAC c.1690_1691delGTinsAC p.V564T RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Protein Effect Treatment Approaches
FGFR2 V564T no effect - predicted