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Gene APC
Variant D1003N
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC D1003N lies within a region of the Apc protein responsible for downregulation mediated by ubiquitination (UniProt.org). D1003N has been identified in sequencing studies (PMID: 25545608, PMID: 23085758), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC D1003N

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Transcript NM_000038.6
gDNA chr5:g.112838601G>A
cDNA c.3007G>A
Protein p.D1003N
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001127510.2 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_001127510 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38
NM_000038 chr5:g.112838601G>A c.3007G>A p.D1003N RefSeq GRCh38/hg38

Filtering

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  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries