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Gene APC
Variant R876Q
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC R876Q does not lie within any known functional domains of the Apc protein (UniProt.org). R876Q has been identified in sequencing studies (PMID: 22895193, PMID: 29684080), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC R876Q

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Transcript NM_000038.6
gDNA chr5:g.112838221G>A
cDNA c.2627G>A
Protein p.R876Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001354895.1 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_000038.6 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_001354899.1 chr5:g.112838304_112838305delAGinsCA c.2626_2627delAGinsCA p.R876Q RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_001354899.2 chr5:g.112838304_112838305delAGinsCA c.2626_2627delAGinsCA p.R876Q RefSeq GRCh38/hg38
NM_001127510 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_000038 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112838221G>A c.2627G>A p.R876Q RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries