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Gene APC
Variant R805Q
Impact List missense
Protein Effect unknown
Gene Variant Descriptions APC R805Q does not lie within any known functional domains of the Apc protein (UniProt.org). R805Q has been identified in sequencing studies (PMID: 31320401), but has not been biochemically characterized and therefore, its effect on Apc protein function is unknown (PubMed, Mar 2024).
Associated Drug Resistance
Category Variants Paths

APC mutant APC R805Q

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Transcript NM_000038.6
gDNA chr5:g.112838008G>A
cDNA c.2414G>A
Protein p.R805Q
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000038.6 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001127510.3 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001127510.2 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001127510 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_000038.5 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001354895.2 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_000038 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001354895.1 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38
NM_001407450.1 chr5:g.112838008G>A c.2414G>A p.R805Q RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
APC R805Q unknown